Pro-domain removal in ASP-2 and the cleavage of the amyloid precursor are influenced by pH
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Background One of the signatures of Alzheimer's disease is the accumulation of aggregated amyloid protein, Aβ, in the brain. Aβ arises from cleavage of the Amyloid...
背景 阿尔茨海默病(Alzheimer's disease)的标志性病理特征之一,为脑内聚集型淀粉样蛋白Aβ(amyloid β, Aβ)的沉积。Aβ由淀粉样蛋白经裂解产生



