Association of cognitive performance with systemic inflammation and mean FA from the region of the corpus callosum that showed significant negative correlation of FA with inflammation in the voxel-wise TBSS analysis.

The results from three types of linear regression models are shown. In the first two columns, the composite measure of systemic inflammation and mean FA are included in models separately. In the last column, the two measures are included in the same model. All linear regression models contain as covariates age, sex, level of education, history of hypertension, and use of antihypertensive medication at evaluation. The estimate (β), standard error (SE) and p-value (p) are reported for each case. Significant associations are in bold letters and the p-value is marked with a *.