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Synthesis of Highly Functionalized Indoles and Indolones via Selectivity-Switchable Olefinations

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NIAID Data Ecosystem2026-03-10 收录
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Highly functionalized indoles and indolones were prepared via selectivity-switchable mono- or diolefinations. The Julia olefination of the products followed by a Brønsted acid-prompted cyclization afforded indolones, whereas the indoles were obtained by a sequential Wittig olefination and electrocyclization. This method opens divergent access to highly functionalized nitrogen-containing bicyclic or tricyclic heterocycles.

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2018-02-05
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