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Additional file 4 of Repurposing a detrimental antibody epitope as targeted therapeutics for sepsis and rheumatoid arthritis

NIAID Data Ecosystem2026-05-10 收录

脓毒症靶向治疗

关节炎靶向治疗

数据链接：

https://figshare.com/articles/dataset/Additional_file_4_of_Repurposing_a_detrimental_antibody_epitope_as_targeted_therapeutics_for_sepsis_and_rheumatoid_arthritis/31360707 数据链接链接失效反馈

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资源简介：

Additional file 4. Primary data

应用场景：

创建时间：

2026-02-17

激酶抑制剂发现

关节炎靶向治疗

Osteoarthritis is the most common joint disorder. However, there are no disease-modifying drugs approved for OA treatment. CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splici

Figshare80

Ex vivo gene transfer in the years to come

基因治疗优化

关节炎靶向治疗

Synovial fibroblasts (SFs) have become a major target for ex vivo gene transfer in rheumatoid arthritis (RA), but efficient transduction of RA-SFs still is a major problem. The low proliferation rate

PubMed Central2001-10-09 更新50

Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis. Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis

RNA药物递送

关节炎靶向治疗

Osteoarthritis (OA) and rheumatoid arthritis (RA) are joint diseases that are associated with pain and lost quality of life. No disease modifying OA drugs are currently available. RA treatments are be

NIAID Data Ecosystem30

Targeting MyD88 Downregulates Inflammatory Mediators and Pathogenic Processes in PBMC From DMARDs-Naïve Rheumatoid Arthritis Patients. Targeting MyD88 Downregulates Inflammatory Mediators and Pathogenic Processes in PBMC From DMARDs-Naïve Rheumatoid Arthritis Patients

关节炎靶向治疗

炎症反应转录组

Purpose: We analyzed RNA-seq from peripheral blood mononuclear cells (PBMC) in DMARDs-naïve RA patients and healthy subjects. Our goal was to evaluate the transcriptional profiles of ST2825-treated PB

NIAID Data Ecosystem60

Route to Rheumatoid Arthritis by Macrophage-Derived Microvesicle-Coated Nanoparticles

关节炎靶向治疗

生物合成纳米颗粒

The targeted delivery of therapeutics to sites of rheumatoid arthritis (RA) has been a long-standing challenge. Inspired by the intrinsic inflammation-targeting capacity of macrophages, a macrophage-d

NIAID Data Ecosystem40

Additional file 4 of Repurposing a detrimental antibody epitope as targeted therapeutics for sepsis and rheumatoid arthritis

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