Changes in kidney function for malignant tumors head and neck after getting chemotherapy cisplatin-based neoadjuvant

Cisplatin is a chemotherapy drug used in the treatment of head and neck malignancies. The main side effect of cisplatin is nephrotoxicity. Nephrotoxicity is characterized by a decrease in the glomerular filtration rate (GFR), an increase in blood urea nitrogen (BUN) and serum creatinine (SK).