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Crystal structure of 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II Descriptor: 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... Authors: Martin, D.P, Cohen, S.M. Deposit date: 2014-04-25 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57, 2014

与人类碳酸酐酶II(human carbonic anhydrase II)结合的1-羟基-3-(三氟甲基)吡啶-2(1H)-硫酮(1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione)的晶体结构 标注项:1-羟基-3-(三氟甲基)吡啶-2(1H)-硫酮、碳酸酐酶2、汞苯甲酸(MERCURIBENZOIC ACID)等 作者:Martin D.P.、Cohen S.M. 提交日期:2014-04-25 发布日期:2015-03-11 最后修改日期:2023-09-20 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.55埃(1.55 Å) 引用文献:探究蛋白质环境对金属结合药效团的影响。《J.Med.Chem.》,57卷,2014年
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2014-04-25
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