SCCA expression correlates to high grade breast carcinoma in the CDP prognostic TMA.

The Stage I (Case Sets 9–13), Stage II (Case Sets 14–17), and Stage III (Case Sets 18–19) prognostic TMAs were obtained from CDP, containing 598, 411, and 184 tissue specimens, respectively. IHC was performed against SCCA. The tissue was scored and the SCCA-positive cases are shown in parentheses against the number of cases in each grade. Note that all of the normal tissue were SCCA-negative, whereas 1 out of 294 Grade I, 11 out of the 534 Grade II, and 29 out of 310 Grade III cases were SCCA-positive.