Mitochondrial Nat10-Kac-axis Play a Vital Role in Carcinogenesis via Acetylation
收藏国家人口健康科学数据中心2026-06-01 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A001G.202601.14.V1.0
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资源简介：
NAT10 is a vital acetyltransferase and mainly localizes in nucleus. Currently, the oncogenic function of nuclear and membranous NAT10 are clear. However, whether NAT10 functions in mitochondrial remains unknown. Here, we found that NAT10 is also localized in mitochondrial and catalyze the acetylaion of multiple enzymes in mitochondrial. Therefore, the mitochondrial NAT10 is a vital therapeutic target for cancer.
提供机构：
北京蛋白质组研究中心
创建时间：
2024-04-10
