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Gene expression profile of HGPS skin fibroblasts upon treatment with JH4

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NIAID Data Ecosystem2026-03-10 收录
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To gain further insight into the biological effects of JH4, we investigated its impact on gene expression profiles. We defined a set of genes such as IL33, BRCA1, BLM, Rad51, IL6, IL8, and TNFSF18 whose expression is restored by JH4 treatment 4 total RNA samples from HGPS, JH4-treated HGPS, young (9-yr; N9) and old (81-yr; N81) fibroblasts are anlayzed. Young fibroblast (9-yr) was used control

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2018-07-26
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