Catalytic Domain of Human Calpain 8 Descriptor: CALCIUM ION, Calpain-8, Leupeptin Inhibitor Authors: Davis, T.L, Paramanathan, R, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith,

Protein Data Bank Japan2024-10-30 更新30

The M1 aminopeptidase NPEPPS is a novel regulator of cisplatin sensitivity

化疗耐药机制

药物靶点发现

Platinum-based chemotherapeutics are used in many combination regimens in cancer. Despite extensive use across diverse cancer types, there is room for improved efficacy and patient selection for treat

NIAID Data Ecosystem10

Additional file 2 of Network analysis of atherosclerotic genes elucidates druggable targets

蛋白质相互作用网络

药物靶点发现

Additional file 2. Protein protein interaction at different confidence score.

Figshare2022-03-04 更新40

The solute carrier superfamily interactome

膜转运蛋白相互作用组

药物靶点发现

Solute carrier (SLC) transporters form a protein superfamily that enables transmembrane transport of a wide range of substrates including nutrients, vitamins, ions and drugs. There are about 450 diffe

Zenodo2025-07-07 更新20

Discovery of a druggable copper-signaling pathway that drives inflammation

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