Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) table for Placenta Full Term, v1.2

Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) tables (https://humanatlas.io/asctb-tables) aim to capture<br>anatomical human body parts, the typology of cells, and biomarkers used to identify cell types. The tables are<br>authored and reviewed by an international team of experts. The Placenta ASCT+B table represents terms related to the<br>full-term human placenta. These include both macroscopic and microscopic anatomical structures, major cell types, and<br>protein and lipid biomarkers specific for each cell type listed. This table was generated based on published placental<br>histopathologic nomenclature, as well as published literature on cell-type specific biomarkers. Most of the markers<br>listed are observed in more than one study or orthogonally validated. Note that these are predicted markers and a<br>single marker to annotate a cell type is not likely sufficient or specific. Where more refined cell types are not<br>available in the ontologies, the closest general term is used. For example, there are likely multiple types of<br>placental stromal cells; however, further characterization is needed to distinguish between these cell types. Where<br>cells of similar type occur in different locations, the closest and highest level of resolution available is used. For<br>example, vascular endothelial cells (CL:0000071) occur in multiple different contexts within the placenta, including<br>the umbilical vessels, chorionic plate vessels, chorionic stem villous vessels and capillaries, and decidual vessels;<br>similarly, vascular smooth muscle cells (CL:0000359) occur in umbilical vessels, chorionic plate vessels, and<br>chorionic stem villous vessels.