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Chromatin and gene expression profile at single nuclei level of CD45+ leukocytes from the rhesus brain parenchyma

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE261968
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We used Chromium Single Cell Multiome ATAC + Gene Expression to analyze CD45+ leukocytes in the rhesus macaque brain during homeostasis and chronic SIV infection Leukocytes (CD45+ cells) of previously cryopreserved rhesus macaque brain single cell suspensions were isolated using MACS CD45 microbeads/column purification followed by Fluorescence-activated cell sorting (FACS) according to the presence of absence of CD45 signal. Nuclei were extracted according to 10x protocols and analyzed using single snATACseq
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2024-09-19
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