Homo sapiens Targeted Locus (Loci). Homo sapiens

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数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA285286 数据链接链接失效反馈

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资源简介：

The goal of this study is to combine truncated gRNAs with RNA-guided FokI nucleases for improved genome editing specificity.

创建时间：

2015-05-29

A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture. A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture

CRISPR脱靶效应

基因组编辑特异性

Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the speci

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Additional file 1 of Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2

CRISPRgRNA设计

基因组编辑特异性

Supplementary Material 1: Supplementary Tables. Table S1: Quantitative and qualitative comparisons of the GuideScan2 algorithm to existing software for gRNA design and analysis. Table S2: Parameters o

DataCite Commons2025-02-27 更新60

Data production and mapping results for the three samples used.

MHC主要组织相容性复合体

基因组编辑特异性

Target regions here refer to contiguous MHC regions, rather than to the region actually covered by the designed probes. Capture specificity is defined as the percentage of uniquely mapped reads aligni

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Additional file 1 of Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2

CRISPRgRNA设计

基因组编辑特异性

Figshare2025-02-27 更新60

Additional file 3: of NmeCas9 is an intrinsically high-fidelity genome-editing platform

CRISPR脱靶分析

基因组编辑特异性

Table S2. Summary of potential off-target sites detected by GUIDE-seq analysis using the Bioconductor package GUIDE-seq. The table includes sites for both NmeCas9 (with N4GN3 PAM sequences) and SpyCas

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Homo sapiens Targeted Locus (Loci). Homo sapiens

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