IRF5 and IRF3 regulate distinct immune programs in plasmacytoid dendritic cells
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108526
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Transcriptomic analyses of pDCs show that the partitioning of TLR/IRF5 and RLR/IRF3 pathways confers differential gene expression and immune cytokine production in pDCs, linking IRF5 with immune regulatory and proinflammatory gene expression. mRNA-seq profiling of plasmacytoid dendritic cells treated with TLR7/8 agonist R848 vs. vehicle; also PAMP (pU/UC) and controls (xRNA) vs. no RNA
创建时间：
2025-01-09
