Abnormal Recovery from Acute Stress in Huntingtons Disease Mice
收藏DataCite Commons2022-03-08 更新2025-04-09 收录
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https://conservancy.umn.edu/handle/11299/194497
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资源简介：
Comparisons of hypothalamic dysfunction between Huntington’s Disease (HD) patients and rodent models of HD have not always yielded similar results. Cortisol levels in HD patients have been contradictory, with reports ranging from hypo- to hypercorticoidism of morning measurements. Initial reports of major elevations in circulating corticosterone levels in the R6/2 mouse model of HD have only been followed up in one other closely related model, the R6/1 mouse, and the results were not perfectly congruent. To determine if abnormal stress hormones were a characteristic of disease, we examined diurnal and stress-induced corticosterone levels in multiple HD mouse models.
提供机构：
Data Repository for the University of Minnesota (DRUM)
创建时间：
2018-03-19
