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Table S1 - HIV Protein Sequence Hotspots for Crosstalk with Host Hub Proteins

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List of motifs defining hotspots per HIV protein. This file is a nine-tab Excel spread sheet containing motifs shared by HIV proteins and some of the neighbors of HIV protein targeted hub proteins. Each tab lists motifs for an HIV protein with its corresponding details. Headings Hub ID and Hub Symbol represent the Entrez ID and gene symbol of the hub protein to which the motif belongs. Pattern is the regular expression of the motif. Info Content is the information content of the motif pattern. The p value is computed by statistical enrichment of the motif among neighbors of the hub protein in comparison to HPRD proteins. The number of neighbors of a hub protein and the neighbors on which the motif is present are shown with the symbols # of H2s and H2s w/Motif, respectively. Start and End headings refer to the start and end positions of the motif on the corresponding HIV protein sequence, calculated based on the most common positions observed on the HIV protein sequences. (XLSX)
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2011-08-15
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