Fixed-Dose Ivermectin for Mass Drug Administration: Is it time to leave the dose pole behind? Insights from an Individual Participant Data Meta-Analysis.

This study is an Individual Participant Data Meta-analysis (IPD MA) that provides a comprehensive assessment of fixed-dose ivermectin regimens, using anthropometric data from over 700,000 participants across 53 countries endemic for STH. IPD were obtained from two main sources: (1) studies on STH interventions conducted in endemic regions and (2) datasets from data repositories, accessed in compliance with their specific protocols.The datasets underwent a five-step process: selection, standardization, compilation, cleaning, and consistency assessment. First, only variables of interest were retained, excluding others from the original studies. Next, standardization ensured consistency across datasets: age was recorded in months (children) or years (adults), weight in kilograms (one decimal), and height in centimetres (one decimal). Each site was coded by country.The resulting datasets organized in three different documents by age group (PSAC, SAC and WRA) and corresponding user-manuals are made available for reuse by other researchers in this data repository.