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Hesse2021 - Interplay between core-clock and cancer drug irinotecan pharmacokinetics and -dynamics

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NIAID Data Ecosystem2026-03-12 收录
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https://www.omicsdi.org/dataset/biomodels/MODEL2109140001
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Refined quantitative core-clock model based on the model by Relógio et al. 2011. The translation-transcription network is extended by a set of irinotecan-relevant genes, which allows to connect the core clock to the irinotecan pharmacokinetics and -dynamics model by Ballesta et al. 2011. The original model by Ballesta et al. 2011 is extended by an explicit simulation of the number of living and dead cells.
创建时间:
2021-09-15
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