Combined conditioned media of probiotics lowered intestinal injury incidence.

A neonatal rat intestinal injury model and disease scoring were conducted as in the “Materials and Methods”. Experimental model rat pups were treated with vehicle or different combination of conditioned media (CM) from Lactobacillus plantarum (Lp), Lactobacillus acidophilus (La), and Bifidobacterium infantis (Bi). Naturally born and dam-fed pups were healthy controls. “*” depicts p<0.05 compared to the vehicle-treated group between the experimental model groups by χ2 test.