Determination of the sensitivity and specificity for the 9 HCC markers.

Notes: For each peak, the mean intensity and standard deviation (SD) were calculated. The cut-off value was defined as the mean plus one SD of those in the HCC group, which was then used to determine the sensitivities and specificities of the HCC. Sensitivity was defined as the ratio of HCC samples with a mass intensity less than cut-off value to all HCC samples, while the specificity was defined as the ratio of CHB samples with a mass intensity greater than the cut-off value to all CHB samples. Validation ability was defined as the ratio of samples with right diagnose according to cutoff value to all samples. AUC was the area of ROC (receiver operator characteristic curve).