Vitamin E in onoxaliplatin-induced neuropathy prevention

Intervention 1: in intervention group :vitamin E 400 mg daily. Intervention 2: Control group were observed.;Prevention;in intervention group :vitamin E 400 mg daily;Control group were observed Primary outcome(s): Peripheral neuropathy. Timepoint: before study and then 3 months later. Method of measurement: questionnaire. Study Design: Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention.