X-ray Structure at 1.75 A Resolution of a Norovirus Protease Linked to an Active Site Directed Peptide Inhibitor

X-ray Structure at 1.75 A Resolution of a Norovirus Protease Linked to an Active Site Directed Peptide Inhibitor Descriptor: N-ACETYL-L-ALPHA-GLUTAMYL-L-PHENYLALANYL-L-GLUTAMINYL-N-[(1S)-4-AMINO-1-(2-CARBOXYETHYL)-4-OXOBUTYL]-L-LEUCINAMIDE, Thiol protease P3C Authors: Hussey, R.J. Deposit date: 2006-10-12 Release date: 2007-10-23 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide Inhibitor. Biochemistry, 50, 2011

分辨率1.75埃的诺如病毒（Norovirus）蛋白酶与活性位点靶向肽抑制剂结合的X射线晶体结构
描述项：N-乙酰-L-α-谷氨酰-L-苯丙氨酰-L-谷氨酰胺酰-N-[(1S)-4-氨基-1-(2-羧乙基)-4-氧代丁基]-L-亮氨酰胺（N-ACETYL-L-ALPHA-GLUTAMYL-L-PHENYLALANYL-L-GLUTAMINYL-N-[(1S)-4-AMINO-1-(2-CARBOXYETHYL)-4-OXOBUTYL]-L-LEUCINAMIDE），巯基蛋白酶P3C
作者：Hussey, R.J.
提交日期：2006-10-12
发布日期：2007-10-23
最后修改日期：2024-11-20
实验方法：X射线衍射（1.75 Å）
引用文献：《诺如病毒3C蛋白酶特异性的结构研究：设计的活性位点靶向肽抑制剂的结合》，《生物化学（Biochemistry）》，第50卷，2011年