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RNA-sequencing of testes from control and Hormad1&2SFB/SFB mice

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP525588
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To examine whether Hormad1&2SFB/SFB (dsfb) male mice has defect in the meiotic sex chromosome inactivation (MSCI) process or not, three pairs of P19 testes were collected from each strain and mRNA-sequencing was performed. The data revealed that the transcription of X and Y chromosomes, but not autosomes, were specifically elevated. Therefore, MSCI was defective in dsfb spermatocytes. Overall design: Three pairs of PD19 testes from different mice were isolated and mRNA-sequencing was performed on the samples.
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2025-03-21
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