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Genomic and Epigenomic Analysis of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Gastric Cancer Progression

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA383939
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资源简介:
Metaplasia of the gastric epithelia (intestinal metaplasia, IM) is a pre-malignant lesion associated with increased gastric cancer (GC) risk. Employing high-depth targeted sequencing of >750 cancer genes and DNA methylation arrays, we surveyed 205 non-malignant gastric tissues including 140 IMs, obtained from 148 cancer-free patients through a 10-year prospective clinical study.
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2017-04-23
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