Proteomics raw data of serum extracellular vesicles from bitches with mammary neoplasia

These data are related to research investigating proteomics in serum extracellular vesicles (EVs) from bitches with mammary neoplasia for comparison to young bitches with no history of neoplasia. Our hypothesis was that neoplasia groups have a different abundance of proteins from the control bitches. We collected blood, separated the serum, isolated the EVs, and then analysis from the EVs' protein cargo. Six proteins had differences in abundance among the groups.本数据集关联的研究针对罹患乳腺肿瘤的母犬血清来源的细胞外囊泡（extracellular vesicles, EVs）开展蛋白质组学（proteomics）分析，并与无肿瘤病史的青年母犬进行对照比较。本研究的核心假设为：肿瘤组母犬与对照组母犬的蛋白质丰度存在差异。我们采集血液样本、分离血清、提取细胞外囊泡，随后对囊泡内的蛋白质载荷开展分析。最终在各组间鉴定出6种丰度存在差异的蛋白质。