WGS of various HAP1 clones that have DNA repair deficiencies and/or were UV irradiated

Genetic variants (Strelka2 calls, excluding recurring variants) accumulated in HAP1 clones during 3 months in culture: two MSH2 k.o. clones; two MLH1 k.o. clones; one wild-type clone; one MLH1 k.o. UV-irradiated clone; one MSH2 k.o. UV-irradiated clone; one wild-type UV-irradiated clone, and one MUTYH k.o. UV-irradiated clone. Cells were exposed to UVC at 5 J/m2 three times, with an interval of 72h following each irradiation.