The IL-17A response of expanded LPMCs to HP-pulsed APCs.

The mean ± SEM (standard error of mean) has been depicted for measurements of IL-17A concentration in the supernatant of co-culture experiments performed as described in the legend for figure 3C. LPMCs were co-cultured with autologous HP-pulsed APCs, either in the absence or presence of MHC Class II blocking antibody. The fold-decrease in response was calculated by dividing the supernatant concentration of IL-17A from the culture without MHC Class II blockade, by the IL-17A concentration in the culture with MHC Class II blockade. The mean fold-decrease was obtained for the indicated number of biological replicates in each group, and mean ± SEM has been reported in the table.