long noncoding RNAs expression in mature and immature dendritic cells-derived exosomes

Dendritic cells release bioactive exosomes that are involved in immune regulation. Long non-coding RNAs (lncRNAs) have been demonstrated to be implicated in many immunoregulatory mechanisms. However, the roles of lncRNAs in dendritic cells-derived exosomes remain unknown. To investigate the roles of lncRNAs in mature and immature dendritic cells-derived exosomes and find specific lncRNAs with immunoregulatory function, this study showed the expression profiles of lncRNAs in bone marrow dendritic cells-derived exosomes from C57 mice. Overall design: We compared lncRNA profiles in two kinds of exosomes derived from immature and mature bone marrow dendritic cells. There are three replicates in each group.