Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in an intermediate-closed state, class II
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Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in an intermediate-closed state, class II Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... Authors: Kwon, D.H, Suo, Y, Lee, S.-Y. Deposit date: 2021-08-08 Release date: 2022-06-01 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. Nat Commun, 13, 2022
冷冻电镜(Cryo-Electron Microscopy, Cryo-EM)解析的全长瞬时受体电位阳离子通道亚家族V成员1(Transient receptor potential cation channel subfamily V member 1, TRPV1)与RTx复合物在4摄氏度下的结构,处于中间闭合态、II类构象。
组分说明:1-棕榈酰-2-油酰-sn-甘油-3-磷酸胆碱、钠离子(SODIUM ION)、瞬时受体电位阳离子通道亚家族V成员1(Transient receptor potential cation channel subfamily V member 1)等。
作者:Kwon, D.H、Suo, Y、Lee, S.-Y.
提交日期:2021-08-08
发布日期:2022-06-01
最后修改日期:2024-11-06
实验方法:冷冻电子显微镜(分辨率3.45埃)
引用文献:基于冷冻电镜集合分析的香草酸依赖型TRPV1激活轨迹,《自然-通讯》(Nat Commun),2022年,第13卷。
创建时间:
2021-08-08



