Alox12

ENCODES a protein that exhibits arachidonate 12(S)-lipoxygenase activity (ortholog); arachidonate 15-lipoxygenase activity (ortholog); linoleate 13S-lipoxygenase activity (ortholog); INVOLVED IN arachidonate metabolic process; cellular response to lipid; hepoxilin biosynthetic process; PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Carotid Artery Injuries; congestive heart failure; hypertension; FOUND IN sarcolemma; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benoxaprofen; bisphenol A

编码一种表现出花生四烯酸12(S)-脂氧合酶活性（同源）；花生四烯酸15-脂氧合酶活性（同源）；亚油酸13S-脂氧合酶活性（同源）的蛋白质；参与花生四烯酸代谢过程；细胞对脂质的响应；肝氧脂生物合成过程；参与阿司匹林药效动力学途径；抗吡啉药物途径；花生四烯酸代谢途径；与颈动脉损伤、充血性心力衰竭、高血压相关；存在于肌膜、细胞质（同源）、细胞溶质（同源）中；与2,3,7,8-四氯二苯并-对-二恶英、苯氧苯丙酸、双酚A相互作用。