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Crystal structure of PDC-3 beta-lactamase in complex with the boronic acid inhibitor LP-06

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Protein Data Bank Japan2024-10-30 更新2026-08-24 收录
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Crystal structure of PDC-3 beta-lactamase in complex with the boronic acid inhibitor LP-06 Descriptor: Beta-lactamase, IMIDAZOLE, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE Authors: Kumar, V, van den Akker, F. Deposit date: 2023-04-07 Release date: 2023-08-16 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrob.Agents Chemother., 2023

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2023-04-07
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