The ETS domain-containing hematopoietic transcription factor PU.1 mediates the induction of arachidonate 5-lipoxygenase by multi-walled carbon nanotubes in macrophages in vitro
收藏ICPSR2025-01-01 更新2026-04-16 收录
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资源简介：
Fibrogenic multi-walled carbon nanotubes (MWCNTs) polarize macrophages to M1 cells with elevated production of proinflammatory lipid mediators (LMs) to boost acute inflammation. Here we examined the mechanism by which MWCNTs (Mitsui-7) induce arachidonate 5-lypoxygenase (Alox5) critical for production of chemotactic LM leukotriene B4 (LTB4) in murine and human macrophages.
提供机构：
National Institute for Occupational Safety and Health
创建时间：
2025-01-01
