Aryl hydrocarbon receptor dynamically regulates immunological and secretory gene pathways in decidual endometrial stromal cells. Aryl hydrocarbon receptor dynamically regulates immunological and secretory gene pathways in decidual endometrial stromal cells

We report mRNA sequencing from decidual stromal cells after 24 hours and 6 days treatment with Aryl Hydrocarbon Receptor (AHR) activators 100 µM L-kynurenine or 10 nM TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin) Overall design: We report mRNA sequencing from samples with 24 hours (n=3) or 6 days (n=2) treatment with Aryl Hydrocarbon Receptor (AHR) activators 100 µM L-kynurenine or 10 nM TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin) that was combined with AHR ChIP-Seq data. Before kynurenine and TCDD treatments endometrial stromal fibroblasts were in vitro decidulization with cAMP and progesterone (MPA) for 2 days. Media and activators were changed every 2 days. The 24 hours control (3 days of decidulization: GSM3138934, GSM3138935 and GSM3138936) and 6 days control (8 days of decidulization: GSM3138937 and GSM3138938) mRNA sequencing samples without AHR activators were submitted previously.