CAD enrichment scores for selected non-overlapping supersets after the merging of CAD-associated canonical pathways and co-expression modules.

The enrichment score was defined as the mean of negative log-transformed Kolmogorov-Smirnov and Fisher P-values for over-representation of high-ranking GWAS SNPs among the eSNPs that affect the expression of the superset member genes.
*P<0.05 in either Fisher's exact test or Kolmogorov-Smirnov test after Bonferroni correction for the 3,539 original gene sets.