Effect of Pterostilbene (PTE) treatment on gene expression after intracerebral hemorrhage injury

To investigate the effect of Pterostilbene(PTE) on gene expression after intracerebral hemorrhage injury, we employed RNA sequencing (RNA-seq) to profile the mRNA expression ensuing PTE treatment after ICH. Different gene distribution could be clearly seen on the volcano plot between diferent comparisions among Sham, ICH, and ICH+PTE group. Finally, we showed that 1021 shared genes overlapping between those differentially expressed genes, which was reversed by PTE treatment Overall design: Experimental mice were randomly and equally divided into three groups: sham group, ICH group, ICH + PTE group. At 3 days after diferent treatments, 3 mice were randomly selected from each group and used to preform RNA sequencing.