Research on virulence regulatory factors of E. cloacae

b-N-acetylglucosaminidase (NagZ), a cytosolic glucosaminidase, plays a pivotal role in peptidoglycan recycling. Previous research demonstrated that NagZ knockout significantly eradicated AmpC-dependent b-lactam resistance in Enterobacter cloacae. However, NagZ's role in the virulence of E. cloacae remains unclear.