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Recombinant Anti-thrombin treatment against endotoxemia-induced acute respiratory distress syndrome (ARDS).

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NIAID Data Ecosystem2026-03-12 收录
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We made LPS induced ARDS model mice, and determined the effect of recombinant anti-thrombin against ARDS. Following 16-h starvation, mice were intraperitoneally injected with LPS (20 mg/kg; MilliporeSigma, Burlington, MA), and in some assays, with saline or recombinant Anti-thrombin (rAT; 750 IU/kg; Kyowa Kirin Co., Ltd, Tokyo, Japan) at 3 and 24 h post-LPS injection. Total RNA was extracted from mouse lung 30h after LPS injection.

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2021-07-20
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