Epigenomic Landscapes Define Differential JAK Inhibitor Sensitivity in IFN-?-Primed Human Macrophages [ATAC-seq]
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP463507
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资源简介：
We analyzed ATAC sequences to demonstrate selective regulation of genetic programs by JAKi in IFN-? primed human macrophages. Overall design: To investigate the suppressive impact of JAK inhibitors (JAKi) on macrophages primed with IFN-?, THP-1 monocytes were co-treated with PMA for differentiation and IFN-? for priming, followed by a JAKi (tofacitinib) treatment.
创建时间：
2025-06-25
