Hnrnpk

The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]

该基因编码的蛋白质是异质核糖核蛋白（hnRNP）复合物的一部分，同时也是一种多胞苷酸结合蛋白（PCBP）。该蛋白存在于多个亚细胞区室中，包括细胞核、细胞质和线粒体。据推测，该基因产物能与RNA、DNA和蛋白质相互作用，并参与多种细胞过程，例如转录、染色质重塑、DNA损伤反应、信号转导、mRNA剪接、输出和翻译。存在多种转录变体和蛋白质异构体，其中某些异构体含有独特的C端。该基因存在四个假基因，分别位于染色体2、3、7和13上。[由RefSeq提供，2014年8月]