Antibody mediated neutralisation of different influenza virus subtypes.

1Neutralisation of laboratory adapted X-181 strain corresponding to A/California/07/2009 (H1N1)pdm09, NIBRG-14 a reverse genetics reassortant of A/Vietnam/1194/2004 (H5N1) with the polybasic cleavage site removed from the HA, NIBRG-147 reverse genetics reassortant of A/Singapore/01/57 (H2N2), NIBRG-91 reverse genetics reassortant of A/chicken/Hong Kong/G9/97 (H9N2), NIBRG-109 reverse genetics reassortant of A/New York/107/2003 (H7N7).
2IC50 is given in nM and is the concentration required to give 50% maximum neutralisation. Data is given as the mean mean of a minimum of three independent assays ± SEM.
3+ indicates neutralisation was seen but a IC50 could not be calculated as a maximum level of neutralisation activity was not reached. 4– indicates no neutralisation. 5 ND is not determined.