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Trypanosoma brucei brucei procyclic and metacylic transcriptome

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NIAID Data Ecosystem2026-05-17 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP103532
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资源简介:
We used an in vitro system to obtain Trypanosoma brucei metacyclics and determined their mRNA repertoires by mRNA sequencing in comparison to non-infectious procyclic trypanosomes. We show that metacyclics are quiescent cells, and we propose that the transition to this quiescent state is a factor in the choice of a minimalistic metacyclic variant surface glycoprotein (VSG) expression site, because it requires fewer cellular resources for activation.
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2017-10-27
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