Additional file 12 of C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation

Additional file 12: Table S4. (A) Dysregulated pathways driven by RELAFUS1target genes in TSS±10kb in 293T-RELAFUS1 cells. (B) Dysregulated pathways driven by RELAFUS1 target genes in TSS ±10kb in H1203-mEPN cells. (C) Dysregulated pathways driven by RELAFUS1-S486E target genes in TSS ±10kb in 293T-RELAFUS1-S486E cells. (D) Up-regulated genes in ST-EPN-RELA relative to ST-EPN-YAP1 subgroup (DEGs: RELAup vs YAP1, logFC>1, FDR < 0.05) (E) Down-regulated genes in ST-EPN-RELA relative to ST-EPN-YAP1 subgroup (DEGs: RELA vs YAP1up, logFC < -1, FDR < 0.05) (F) Up-regulated pathways in ST-EPN-RELA subgroup (G) Up-regulated pathways in ST-EPN-YAP1 subgroup. (XLSX 546 KB)