首页/数据集/Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level

Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level

NIAID Data Ecosystem2026-03-14 收录

tRNA充电调控

氨基酸感应信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE188862 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-02-06

tRNA充电调控

细菌严紧反应

Summary Aminoacyl-tRNA synthetases (aaRSs) serve a dual role in charging tRNAs. Their enzymatic activities both provide protein synthesis flux and reduce uncharged tRNA levels. Although uncharged tRNA

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Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level V. Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level V

tRNA充电调控

氨基酸饥饿响应

We profiled the cellular tRNA charging landscape using next-generation sequencing and identified a subset of tRNA that sense nutrients. The charging levels of tRNAGln were exclusively and significantl

NIAID Data Ecosystem20

Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level VI

tRNA充电调控

氨基酸饥饿响应

NIAID Data Ecosystem10

GCN2 adapts the proteome to scavenging-dependent growth

细胞代谢调控

氨基酸感应信号通路

We report the transcriptional and translational changes that occur upon leucine deprivation +/- GCN2. KRPC-A cells (Gcn2 WT and KO) are switched to amino acid-replete or leucine-free medium for one ho

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Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level I

tRNA充电调控

氨基酸饥饿响应

NIAID Data Ecosystem10