MethylationEPIC array of DNMT1 inhibitor treated AML cell lines - part II
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE135206
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资源简介:
Genome wide demethylation by DNMT1 inhibitor GSK3484862 results in up-regulation of epigenetically-silenced genes. Methylation was assayed for each cell line following DNMT1 inhibitor or vehicle treatment. Global methylation distributions were compared between treated and untreated samples. Seven AML cell lines were treated for 96 hours in biological duplicate with 0.1% DMSO or 1 µM GSK3484862 before isolating gDNA, labeling, and hybridizing to MethylationEPIC arrays.
创建时间:
2021-11-30



