Homo sapiens Genome sequencing

Background: Keloid disorder (KD) is a group of fibroproliferative skin disorders characterized by hypervascularity and excessive accumulation of the extracellular matrix (ECM) and affects individuals of all age groups. The etiology of KD is complex and still poorly understood. This study aimed to investigate biomarkers and therapeutic targets in KD on the basis of comprehensive bioinformatics analysis and machine learning of RNA autosequencing data.