Chromosome 22
收藏国家生物信息中心2025-10-11 更新2025-03-15 收录
下载链接：
http://array.mbb.yale.edu/chr22
下载链接
链接失效反馈官方服务：
资源简介：
A DNA microarray representing nearly all of the unique sequences of human Chromosome 22 was constructed and used to measure global-transcriptional activity in placental poly(A)(+) RNA. We found that many of the known, related and predicted genes are expressed. More importantly, our study reveals twice as many transcribed bases as have been reported previously. Many of the newly discovered expressed fragments were verified by RNA blot analysis and a novel technique called differential hybridization mapping (DHM). Interestingly, a significant fraction of these novel fragments are expressed antisense to previously annotated introns. The coding potential of these novel expressed regions is supported by their sequence conservation in the mouse genome. This study has greatly increased our understanding of the biological information encoded on a human chromosome.
提供机构：
Yale University
创建时间：
2018-02-09
