NCBI Gene

Gene supplies gene-specific connections in the nexus of map, sequence, expression, structure, function, citation, and homology data. Unique identifiers are assigned to genes with defining sequences, genes with known map positions, and genes inferred from phenotypic information. These gene identifiers are used throughout NCBI's databases and tracked through updates of annotation. Gene includes genomes represented by NCBI Reference Sequences (or RefSeqs) and is integrated for indexing and query and retrieval from NCBI's Entrez and E-Utilities systems. Gene comprises sequences from thousands of distinct taxonomic identifiers, ranging from viruses to bacteria to eukaryotes. It represents chromosomes, organelles, plasmids, viruses, transcripts, and millions of proteins.

Gene数据库可在基因图谱、序列、基因表达、基因结构、生物学功能、文献引用及同源性数据的交叉范畴内，提供基因特异性关联信息。针对具备特征序列、已知基因图谱定位位点以及通过表型信息推导得到的基因，系统将为其分配唯一标识符。此类基因标识符会在NCBI的全部数据库中全程使用，并伴随注释更新的全流程进行追踪维护。Gene数据库涵盖以NCBI参考序列（Reference Sequences，RefSeqs）为代表的基因组数据，并针对NCBI的Entrez检索系统与E-Utilities工具集的索引、查询及检索需求完成了集成适配。该数据库包含来自数千个不同分类学标识符的序列数据，覆盖范围从病毒、细菌直至真核生物，涵盖染色体、细胞器、质粒、病毒、转录本以及数百万种蛋白质相关数据。

搜集汇总

背景与挑战

背景概述

NCBI Gene是一个提供基因特异性连接的数据集，整合了图谱、序列、表达、结构、功能、引用和同源性数据，并为具有定义序列、已知图谱位置或表型信息的基因分配唯一标识符。它覆盖从病毒到真核生物的多种分类群，包括染色体、细胞器、质粒、病毒、转录本和蛋白质，并集成到NCBI的Entrez和E-Utilities系统中进行索引和查询。