Exploring the Mechanism of Xianggou Polysaccharide in the Treatment of Nonalcoholic Fatty Liver Disease in Mice Based on Proteomics

Nonalcoholic fatty liver disease (NAFLD) is primarily characterized by lipid deposition in hepatocytes, and its incidence is increasing annually, with currently limited treatment options available. Xianggou is a well-known medicinal and edible herb in China, traditionally used for its effects in invigorating the spleen, promoting appetite, and dispelling wind-dampness. In this study, polysaccharides were isolated and purified from Xianggou. Furthermore, the therapeutic mechanism of Xianggou polysaccharides in treating NAFLD was investigated using proteomics.