Variants in the CaMKIV gene are associated with nicotine dependence.

Human genetic association meta-analysis using two datasets (SAGE and MGS, n = 3,969). The variant rs919334 is associated with a protective effect in the FTND score analysis, while rs9285875 is associated with risk for higher FTND scores. The table contains uncorrected p-values, where significant p- values are bolded and underlined. No markers survived correction for multiple testing. Significant Q p-values are italicized. SNP, single nucleotide polymorphism; the Allele column represents the minor allele; Q p-values represent Cochrane’s Q-statistic p-values.