CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling
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https://www.ncbi.nlm.nih.gov/sra/SRP275829
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资源简介：
We report that loss of CCM3/PDCD10 in fibroblasts induces FAK/Src-paxillin signalling driving actomyosin-dependent mechanotransduction leading to YAP/TAZ signalling. In vivo, loss of CCM3 in fibroblasts drives excessive tissue remodelling leading to the dissemination of breast cancer cells to distant organs. Overall design: Examination of the varying RNA levels in control human vulval cancer-associated fibroblasts versus CCM3-depleted cells
创建时间：
2021-07-27
